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Home » Best Joint Supplements in 2022: Our Top 3 Picks

Best Joint Supplements in 2022: Our Top 3 Picks

Best Joint Supplements

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Looking to ease joint inflammation, enhance comfort, and improve overall joint function? Here’s our list of the top 3 best joint supplements in 2022!

If you aren’t already familiar with them, joint supplements are dietary supplements that support the function of your joints and connective tissues by increasing flexibility, protecting cartilage & connective tissues from damage, and reducing enzymes and other factors that cause your joints to hurt and become inflamed.

All of the supplements featured on this list have been thoroughly analyzed to ensure they are effective, safe, and free of any side effects or suspect ingredients.

We base our list on:

  • 100% natural ingredients
  • Fast pain relief
  • Connective tissue support
  • Flexibility & mobility enhancement
  • Long-term cartilage recovery
  • Protection from everyday wear and tear associated with aging
  • Safe, vegan, premium-quality ingredient profile
  • Brand reputation & trustworthiness

It is important to realize that joint supplements are not a miracle panacea. You will still need to get your basics right. An anti-inflammatory diet with regular physical activity (as much as your body allows), along with quality sleep and exposure to sunshine when possible.

However, adding a quality joint supplement to an already healthy routine can be massively beneficial in terms of reducing your joint pain and improving your overall quality of life. Certain ingredients in joint supplements are well-researched and known to quench joint inflammation, promote cartilage repair, and improve long-range joint health.

We’ve inspected over 30 popular joint supplements in the past year alone, comparing them against one another to see which brings the best value. The result of our search has enabled us to present the 3 best joint supplements on the market today.

1. Physio Flex Pro – Best Overall

Physio Flex Pro

Physio Flex Pro is an exciting and highly effective joint supplement made by a specialist supplement company from the U.K., SRS Nutra. It’s been getting a lot of positive attention online, and after reviewing it for ourselves, we can testify it’s currently one of the best – if not the best – supplements you can buy to improve joint comfort and mobility today.

Physio Flex Pro ticked all of our boxes in terms of;

  • Ingredient choice & dosages
  • Effectiveness at reducing inflammation, pain, and mobility issues
  • Safe & natural formula

Every one of the 8 ingredients in Physio Flex Pro has its purpose; each one is backed by robust clinical evidence. There are no harmful fillers or unnecessary junk in Physio Flex Pro, making the formula clean and healthy for everyday use.

The dosages are on point, too. This includes the 4 key ingredients of Physio Flex Pro which include: Glucosamine, Chondroitin Sulfate, MSM, Turmeric, and BioPerine. Together, they work to give you relief from chronic aches, pain, and inflammation, while also protecting your joints and connective tissues from breakdown.

As we mentioned, Physio Flex Pro enjoys excellent reviews online. It is backed by orthopedic experts and physiotherapists from around the world, including the respected Dr. Kavita who specializes in musculoskeletal conditions.

While it’s a premium-priced product, you do get what you pay for with Physio Flex Pro, with no production costs being spared by SRS Nutra. For the cost of $2.06 per day, we’re inclined to agree with other positive reviews – Physio Flex Pro is not a cheap product, but it’s definitely worth the investment if you can afford it.


  • 8 natural ingredients clinically shown to combat joint pain, improve flexibility, and repair cartilage
  • Effective at reducing pain & inflammation
  • Clean and side-effect-free ingredient profile
  • Manufactured in the USA in the gold-standard cGMP- and FDA-approved factories
  • Excellent reviews; endorsed by professionals


Interested in Physio Flex Pro?

– Click Here to Get Prices –

2. Performance Lab Flex – Best for Recovery from Exercise

Performance Lab Flex

Coming in second on our list, Performance Lab Flex is by no means inferior to any other supplement on this list. In fact, it’s arguably the cleanest-quality formula we’ve seen in a joint supplement.

Performance Lab is a company that prides itself on producing their own in-house patented ingredients. The ingredients in Flex are extremely safe, well-researched, and dosed lightly but effectively to make it ideal for long-term joint support.

You can expect the following benefits after using Performance Lab Flex consistently for a few months;

  • Improved shock absorption and connective tissue lubrication
  • Reduction in joint aches and inflammation
  • Faster recovery from exercise
  • Stronger ligaments and tendons
  • Improved motility and flexibility

We’ve mentioned that it might take a month or two for you to start noticing these benefits because joint supplements usually take time to work. This is due to the fact that cartilage and other joint tissues need time to recover from damage and inflammation which causes chronic pain. Having said that, you may very well start to notice the positive effects of Performance Lab Flex as soon as a few days into supplementation, as many people do.

In terms of the reviews, we’re yet to find a single negative testimonial of Performance Lab Flex. Just like other supplements in this guide, Performance Lab Flex is incredibly well-received amongst customers. Its premium-quality formula and optimal ingredient dosages mean high effectiveness and extremely low risk of negative reactions.

The ingredients in Performance Lab Flex include:

  • AprèsFlex® Boswellia Serrata
  • CurcuWIN® Curcumin, 250 mg
  • Glucosamine Sulfate 2KCI
  • Mythocondro® Chondroitin Sulfate
  • OptiMSM® Methylsulfonylmethane (MSM)
  • NutriGenesis® Strontium

As you’ll notice, the ingredients in Performance Flex are completely natural and come in their purest, maximally bioavailable forms. The capsules are made of 100% fermented tapioca fiber, which helps you absorb and digest the ingredients more easily.

Obviously, such an advanced formula with high-quality ingredients raises the production costs for the manufacturer.

In other words, Performance Lab Flex is not cheap! This is why it’s 2nd on our list. But, if you are looking for arguably the absolute best quality joint supplement on the market, Performance Lab Flex is worth looking into.


  • Highest-quality ingredients available
  • 6 patented ingredients
  • Provides a unique effect of shock & impact absorption (useful for people who exercise often)
  • Clean and safe pain reduction effects
  • Excellent bulk-buy discounts


Interested in Performance Lab Flex?

– Click Here to Get Prices –

3. ProJoint Plus – The Cheapest Option

Coming in third is ProJoint Plus, a simple but effective joint supplement made by a well-known American manufacturer VitaPost.

ProJoint Plus

ProJoint Plus ticked most of our boxes when it comes to the ingredients we’re looking for. It contains the basic glucosamine, chondroitin, MSM, and turmeric. While ProJoint Plus is not the most advanced formula we’ve seen, it’s definitely far ahead of many other options on the market today.

ProJoint Plus should give you a reduction in pain and inflammation, along with potentially improving your flexibility.

The main reason why ProJoint Plus didn’t make it higher on our list is that some of its ingredients are a bit on the lighter side. For example, ProJoint Plus contains only 25mg of MSM, whereas our number one pick on this list contains 100mg. This means that the benefits you will experience from ProJoint Plus may not be as substantial as those of other supplements in this guide.

However, for the price of $29.95 per bottle which lasts 2 weeks (or $52.95 for a 30-day supply), ProJoint Plus is the cheapest option on this list. So if the price is the main factor, ProJoint Plus is the one you may consider.


  • Helps to diminish chronic joint pain
  • Simple and straightforward ingredient formula
  • The least expensive option on this list


  • Missing some core ingredients
  • Some key ingredients, such as MSM, are a bit underdosed

Interested in ProJoint Plus?

– Click Here to Get Prices –